Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944600 | 0.91 | ALOX5 (0.41) | PKMKDM4EGRM2ALOX5RAD52 | |
| SCHEMBL25944855 | 0.90 | PRMT5 (0.42) | PKMKDM4EALOX5BDKRB1RAD52 | |
| SCHEMBL25944006 | 0.89 | ALOX5 (0.40) | PKMKDM4EGRM2ALOX5RAD52 | |
| SCHEMBL25945695 | 0.89 | GRM2 (0.40) | PKMKDM4EGRM2ALOX5RAD52 | |
| SCHEMBL25944493 | 0.87 | KDM4E (0.40) | PKMKDM4EGRM2ALOX5RAD52 | |
| SCHEMBL25944785 | 0.86 | PRMT5 (0.41) | PKMKDM4EALOX5RAD52ALDH1A1 | |
| SCHEMBL25939336 | 0.86 | PKM (0.43) | PKMKDM4EALOX5BDKRB1RAD52 | |
| SCHEMBL25945611 | 0.86 | ALOX5 (0.41) | KDM4EALOX5RAD52ALDH1A1MEN1 | |
| SCHEMBL25945920 | 0.85 | ALOX5 (0.41) | KDM4EALOX5RAD52ALDH1A1MEN1 | |
| SCHEMBL25943587 | 0.85 | AAK1 (0.40) | PKMKDM4EGRM2ALOX5RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |