Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25945611 | 0.94 | ALOX5 (0.41) | ALOX5KDM4EMDM2PRMT5WDR77 | |
| SCHEMBL25945695 | 0.91 | GRM2 (0.40) | ALOX5KDM4EELANEALDH1A1HPGD | |
| SCHEMBL25944855 | 0.89 | PRMT5 (0.42) | ALOX5KDM4EPRMT5WDR77ALDH1A1 | |
| SCHEMBL25945764 | 0.88 | ALOX5 (0.41) | ALOX5KDM4EPRMT5WDR77ALDH1A1 | |
| SCHEMBL25945921 | 0.88 | ALOX5 (0.42) | ALOX5KDM4EELANEALDH1A1HPGD | |
| SCHEMBL25944493 | 0.88 | KDM4E (0.40) | ALOX5KDM4EELANEALDH1A1HPGD | |
| SCHEMBL25944600 | 0.87 | ALOX5 (0.41) | ALOX5KDM4EALDH1A1HPGDRAD52 | |
| SCHEMBL25944270 | 0.87 | RAD52 (0.41) | ALOX5KDM4EELANEALDH1A1TSHR | |
| SCHEMBL25945247 | 0.85 | PKM (0.42) | ALOX5KDM4EALDH1A1RAD52MEN1 | |
| SCHEMBL25944785 | 0.85 | PRMT5 (0.41) | ALOX5KDM4EMDM2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |