SCHEMBL25945313

SCHEMBL25945313

Cc1cc(-c2ccc3c(c2)c2ccccc2n3-c2ccc(-c3cccc4c5ccccc5n(-c5ccccc5)c34)cc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc(C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.33
ENPP1 P22413 1/20 0.32
LMNA P02545 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
POLB P06746 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
PIK3CA P42336 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25945316 1.00 PTGER4 (0.33) PTGER4ENPP1LMNAABCG2ALDH1A1
SCHEMBL25945318 0.94 MAT2A (0.32) ENPP1LMNAABCG2ALDH1A1NPSR1
SCHEMBL22586369 0.94 ABCG2 (0.34) PTGER4LMNAABCG2ALDH1A1NPSR1
SCHEMBL22586372 0.94 ABCG2 (0.34) PTGER4LMNAABCG2ALDH1A1NPSR1
SCHEMBL25945098 0.93 PTGER4 (0.35) PTGER4LMNAABCG2ALDH1A1NPSR1
SCHEMBL25945105 0.92 PTGER4 (0.35) PTGER4LMNAABCG2ALDH1A1NPSR1
SCHEMBL25945706 0.92 PTGER4 (0.32) PTGER4ENPP1LMNAABCG2POLB
SCHEMBL22586985 0.92 PTGER4 (0.36) PTGER4LMNAABCG2ALDH1A1NR3C1
SCHEMBL27440421 0.92 ABCG2 (0.35) ENPP1LMNAABCG2ALDH1A1POLB
SCHEMBL25945305 0.92 PTGER4 (0.36) PTGER4LMNAABCG2ALDH1A1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230278992-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
US-11718608-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718608-B2 Organic molecules for use in optoelectronic devices OR10J3, AOX1, ALDH1A2 PTGER4 1409/4885ENPP1 3224/4885LMNA 4110/4885
US-20230278992-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, AOX1, ALDH1A2 PTGER4 1427/4885ENPP1 2990/4885LMNA 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.