Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24440831 | 0.88 | BACE1 (0.44) | KDM4EMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18308840 | 0.86 | BACE1 (0.47) | KDM4EMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25945455 | 0.83 | KDM4E (0.38) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL25933709 | 0.83 | ALOX15 (0.40) | KDM4EMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL17521747 | 0.82 | BACE1 (0.48) | KDM4EMAPTKMT2ASMN1; SMN2BACE1 | |
| SCHEMBL17625853 | 0.82 | ELANE (0.47) | KDM4EMAPTKMT2ARAB9AMAPK1 | |
| SCHEMBL17546774 | 0.81 | KMT2A (0.42) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL17794408 | 0.81 | BACE1 (0.39) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL21469992 | 0.81 | ELANE (0.43) | KDM4EMAPTKMT2ANPC1RAB9A | |
| SCHEMBL20275237 | 0.81 | CYP1A2 (0.50) | KDM4EMAPTKMT2ASMN1; SMN2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056667-B1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-02 | — | — | EP | disclosed |