Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24440894 | 0.91 | AMY1A (0.41) | MAPTPTGS2AMY1APRKCZERN1 | |
| SCHEMBL18699583 | 0.89 | AR (0.42) | PTGS2AMY1APRKCZERN1 | |
| SCHEMBL26144314 | 0.87 | ERN1 (0.42) | MAPTMAPK1RAB9APTGS2AMY1A | |
| SCHEMBL26144313 | 0.87 | ERN1 (0.42) | MAPTMAPK1RAB9APTGS2AMY1A | |
| SCHEMBL25945446 | 0.86 | AMY1A (0.39) | MAPTPTGS2AMY1ACTSAFFAR1 | |
| SCHEMBL15338821 | 0.86 | GAPDH (0.41) | KDM4EMEN1KMT2AHSD17B10ERN1 | |
| SCHEMBL25933764 | 0.86 | FGFR1 (0.40) | MAPTPTGS2AMY1ACTSAFFAR1 | |
| SCHEMBL24440978 | 0.85 | FDPS (0.37) | KDM4EMAPTMAPK1NPC1RAB9A | |
| SCHEMBL15338898 | 0.85 | GAPDH (0.40) | KDM4EMEN1KMT2AHSD17B10ERN1 | |
| SCHEMBL25945385 | 0.83 | KDM4E (0.39) | KDM4EMAPTMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056667-B1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-02 | — | — | EP | disclosed |