Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25951609 | 0.90 | LMNA (0.57) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL25948396 | 0.87 | KMT2A (0.61) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL25948348 | 0.84 | LMNA (0.64) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL31110599 | 0.81 | LMNA (0.56) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL31110603 | 0.81 | LMNA (0.56) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL31110609 | 0.81 | LMNA (0.56) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL31110612 | 0.81 | LMNA (0.56) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL31110564 | 0.80 | L3MBTL1 (0.54) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL25951612 | 0.80 | LMNA (0.50) | LMNAKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL25951686 | 0.78 | KMT2A (0.51) | LMNAKMT2ATDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147161-A2 | NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF | New Frontier Bio, Inc. (US) | 2023-08-03 | — | — | WO | disclosed |