Parbendazole

Parbendazole

SCHEMBL27363030

CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 8/20 1.00
TUBB P07437 8/20 1.00
TUBA3C P0DPH7 8/20 1.00
TUBA1B P68363 8/20 1.00
TUBA4A P68366 8/20 1.00
TUBB4B P68371 8/20 1.00
TUBB3 Q13509 8/20 1.00
TUBB2A Q13885 8/20 1.00
TUBB8 Q3ZCM7 8/20 1.00
TUBA3E Q6PEY2 8/20 1.00
TUBA1A Q71U36 8/20 1.00
TUBA1C Q9BQE3 8/20 1.00
TUBB6 Q9BUF5 8/20 1.00
TUBB2B Q9BVA1 8/20 1.00
TUBB1 Q9H4B7 8/20 1.00
LMNA P02545 7/20 1.00
CYP1A2 P05177 5/20 1.00
HIF1A Q16665 4/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Parbendazole SCHEMBL259456 1.00 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Parbendazole SCHEMBL259455 0.90 TUBB4A (0.82) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Parbendazole SCHEMBL29409286 0.90 TUBB4A (0.82) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753124 0.90 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29511469 0.90 TUBB4A (0.91) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753130 0.90 TUBB4A (0.91) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30785779 0.90 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753108 0.89 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29511339 0.89 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11212646 0.88 TUBB4A (0.78) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173331-A Process for production of anthelmintic composition for animal use PFIZER (US) 1998-02-18 CN claimed
CN-1053549-A Antiparasitic composition for animals SMITHKLINE BEECHAM CORP (US) 1991-08-07 CN claimed
WO-2025087695-A1 METHOD FOR PRODUCING RECOMBINANT ADENO-ASSOCIATED VIRUS PARTICLES ASCEND ADVANCED THERAPIES LTD (GB) 2025-05-01 WO disclosed
CN-105884693-B The composition of Parasiticidal comprising benzimidizole derivatives, method and purposes Merria Co., Ltd. (US) 2019-11-01 CN disclosed
CN-110381738-A Pesticide and Parasiticidal vinyl isoxazoline compound 勃林格殷格翰动物保健美国公司 2019-10-25 CN disclosed
CN-110167921-A ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS 勃林格殷格翰动物保健美国公司 2019-08-23 CN disclosed
CN-105980366-B Six-membered C-N-linked aryl thioether derivatives and aryl sulfoxide derivatives as pest control agents 拜耳作物科学股份公司 2018-12-14 CN disclosed
CN-105232529-B The Moxidectin preparaton and Moxidectin crystal form of long-acting injectable 梅里亚有限公司 2018-11-23 CN disclosed
CN-105732511-B Include the composition of the Parasiticidal of benzimidizole derivatives, method and purposes 梅里亚有限公司 2018-08-17 CN disclosed
CN-104884453-B Anthelmintic compounds and compositions and methods of using the same 梅里亚股份有限公司 2018-06-22 CN disclosed
CN-106661022-B Pyrazolopyridine sulfonamides as nematicides 拜耳作物科学股份公司 2018-05-04 CN disclosed
CN-104202985-A Topical compositions comprising fipronil and permethrin and methods of use MERIAL LTD 2014-12-10 CN disclosed
CN-104053660-A Long-acting injectable moxidectin formulations and novel moxidectin crystalline forms MERIAL LTD 2014-09-17 CN disclosed
CN-104023720-A Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof MERIAL LTD 2014-09-03 CN disclosed
CN-103957701-A Parasiticidal compositions comprising isoxazoline active agents, methods and uses thereof MERIAL LTD 2014-07-30 CN disclosed
CN-102869253-A Parasiticidal compositions comprising multiple active agents, methods and uses thereof MERIAL LTD 2013-01-09 CN disclosed
CN-102741247-A Antiparasitic dihydropyrrole compounds and compositions containing the same MERIAL LTD 2012-10-17 CN disclosed
CN-101773467-A Milbemycin or milbemycin oxime sustained-release injection for animals and preparation method BEIJING DABEINONG ANIMAL HEALT 2010-07-14 CN disclosed
CN-1173331-A Process for production of anthelmintic composition for animal use PFIZER (US) 1998-02-18 CN disclosed
CN-1053549-A Antiparasitic composition for animals SMITHKLINE BEECHAM CORP (US) 1991-08-07 CN disclosed