Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946926 | 0.96 | TSHR (0.47) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25949826 | 0.89 | RAD52 (0.50) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25947457 | 0.87 | TSHR (0.48) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25947857 | 0.87 | RAD52 (0.47) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25946425 | 0.86 | ALOX5 (0.47) | TSHRALDH1A1KMT2AMAPTALOX5 | |
| SCHEMBL25946350 | 0.85 | TSHR (0.51) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25947900 | 0.85 | PKM (0.44) | TSHRALDH1A1KMT2AMAPTPKM | |
| SCHEMBL25948907 | 0.85 | RAD52 (0.48) | TSHRALDH1A1KMT2AMAPTGPR55 | |
| SCHEMBL25949559 | 0.84 | ALOX5 (0.44) | TSHRALDH1A1KMT2AMAPTPKM | |
| SCHEMBL25939725 | 0.83 | RAD52 (0.45) | TSHRALDH1A1KMT2AMAPTGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |