Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | CTRC | Q99895 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174440 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAL3MBTL1PRSS1 | |
| SCHEMBL665537 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAPRSS1CTRC | |
| SCHEMBL9263926 | 0.77 | FAAH (0.36) | ALDH1A1MAPTGAAL3MBTL1KMT2A | |
| SCHEMBL9436209 | 0.76 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL15423555 | 0.73 | — | — | |
| SCHEMBL29886436 | 0.73 | — | — | |
| SCHEMBL2051321 | 0.73 | — | — | |
| SCHEMBL3942028 | 0.73 | — | — | |
| SCHEMBL11431438 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1PRSS1CTRC | |
| SCHEMBL9271157 | 0.73 | NOS2 (0.37) | ALDH1A1MAPTGAAL3MBTL1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810079-A | A kind of synthetic method of polysubstituted dihydrofuran | 浙江工业大学 | 2019-05-28 | — | — | CN | claimed |
| CN-109810079-A | A kind of synthetic method of polysubstituted dihydrofuran | 浙江工业大学 | 2019-05-28 | — | — | CN | disclosed |
| US-8883935-B2 | High refractive index composition | BATTELLE MEMORIAL INSTITUTE (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2563826-A2 | HIGH REFRACTIVE INDEX COMPOSITION | Battelle Memorial Institute (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046054-A1 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
| WO-2011139856-A2 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20090062401-A1 | DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | UNIVERSITAT DORTMUND (DE) | 2009-03-05 | — | — | US | disclosed |
| EP-1841723-A1 | DECALINE DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | Universität Dortmund (DE) | 2007-10-10 | — | — | EP | disclosed |
| EP-1332132-B1 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | UCB PHARMA SA (BE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006069787-A1 | DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | Universität Dortmund (DE) | 2006-07-06 | — | — | WO | disclosed |
| US-4045452-A | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor | HOFFMANN-LA ROCHE INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4044005-A | Peroxides of 2-oxo-cyclopenta[b]furans | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-4032520-A | SYNTHESIS OF CYCLOPENTANOL | KIENZLE FRANK | 1977-06-28 | — | — | US | disclosed |
| US-4029674-A | 2-Oxo-2H cyclopenta[b]furans | HOFFMANN-LA ROCHE INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4005110-A | 2H-Cyclopenta(b)furan-2-ones | HOFFMANN-LA ROCHE INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001281-A | 2-Oxo-cyclopenta[b]furan-5α-carboxylic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994930-A | MULTISTEP, STEREOSPECIFIC TOTAL SYNTHESIS OF STEROIDS | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3991084-A | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor | HOFFMANN-LA ROCHE INC. (US) | 1976-11-09 | — | — | US | disclosed |
| US-3989724-A | Tetrahydropyran-2-ols | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3965138-A | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062401-A1 | DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | CHAT, DLAT, CPT1A | ALDH1A1 1533/4885MAPT 17/4885GAA 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.