Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23892335 | 1.00 | ABL1 (0.37) | ABL1RIN1PDPK1ALDH1A1LMNA | |
| SCHEMBL18571923 | 0.95 | PDPK1 (0.40) | ABL1RIN1PDPK1ALDH1A1LMNA | |
| SCHEMBL18572228 | 0.95 | PDPK1 (0.40) | ABL1RIN1PDPK1ALDH1A1LMNA | |
| SCHEMBL22002163 | 0.81 | PDPK1 (0.37) | PDPK1GPR119JAK3 | |
| SCHEMBL25949266 | 0.81 | PDPK1 (0.37) | PDPK1GPR119JAK3 | |
| SCHEMBL22002066 | 0.80 | PDPK1 (0.36) | PDPK1GPR119JAK3 | |
| SCHEMBL23892341 | 0.80 | PDPK1 (0.36) | PDPK1GPR119JAK3 | |
| SCHEMBL22799584 | 0.80 | ALDH1A1 (0.50) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL18571622 | 0.80 | ALDH1A1 (0.50) | ABL1RIN1ALDH1A1LMNAALB | |
| SCHEMBL18571908 | 0.77 | METTL3 (0.39) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219496-A1 | NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |