Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24070189 | 0.88 | ANO1 (0.43) | KDM4CFTOALKBH5KDM4EKDM6B | |
| SCHEMBL30211949 | 0.88 | ANO1 (0.43) | KDM4CFTOALKBH5KDM4EKDM6B | |
| SCHEMBL25338229 | 0.78 | KDM4C (0.46) | KDM4CKDM4EKDM4AKDM5AKDM5B | |
| SCHEMBL24070745 | 0.76 | KDM4C (0.47) | KDM4CKDM4EALDH1A1MRGPRX4PPARA | |
| SCHEMBL13264471 | 0.74 | GABRP (0.48) | KDM4CMRGPRX4PPARACA1CA2 | |
| SCHEMBL29934030 | 0.73 | KDM4C (0.43) | KDM4CMRGPRX4PPARA | |
| SCHEMBL28884710 | 0.73 | KDM4C (0.43) | KDM4CMRGPRX4PPARA | |
| SCHEMBL6236560 | 0.72 | FTO (0.74) | KDM4CFTOALKBH5KDM4EKDM6B | |
| SCHEMBL23501594 | 0.72 | POLB (0.44) | KDM4CKDM4EALDH1A1MAPTPPARA | |
| SCHEMBL29934040 | 0.72 | POLB (0.44) | KDM4CKDM4EALDH1A1MAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | DDR2, DDR1, DDRGK1 | KDM4C 1477/4885FTO 4358/4885ALKBH5 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.