Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884710 | 1.00 | KDM4C (0.43) | KDM4CKCNH2KCNA5CYP11B2ABL1 | |
| SCHEMBL31359374 | 0.90 | MKNK1 (0.38) | KDM4CKCNH2CYP11B2ABL1SRC | |
| SCHEMBL28884685 | 0.89 | ABL1 (0.44) | KDM4CCYP11B2ABL1SRCALPL | |
| SCHEMBL29934041 | 0.84 | KCNH2 (0.43) | KDM4CKCNH2KCNA5CYP11B2ABL1 | |
| SCHEMBL29932961 | 0.82 | CNR1 (0.42) | — | |
| SCHEMBL29932952 | 0.82 | CNR1 (0.42) | — | |
| SCHEMBL23501594 | 0.81 | POLB (0.44) | KDM4CPPARA | |
| SCHEMBL29934040 | 0.81 | POLB (0.44) | KDM4CPPARA | |
| SCHEMBL24070745 | 0.80 | KDM4C (0.47) | KDM4CPPARAMRGPRX4 | |
| SCHEMBL25338229 | 0.80 | KDM4C (0.46) | KDM4CMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |