Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949173 | 0.85 | — | — | |
| SCHEMBL23892580 | 0.79 | GPR119 (0.33) | JAK3GPR119METTL3 | |
| SCHEMBL25949326 | 0.76 | GPR119 (0.33) | JAK3GPR119METTL3 | |
| SCHEMBL18571703 | 0.76 | GPR119 (0.34) | GPR119 | |
| SCHEMBL18571923 | 0.76 | PDPK1 (0.40) | JAK3GPR119 | |
| SCHEMBL18572228 | 0.76 | PDPK1 (0.40) | JAK3GPR119 | |
| SCHEMBL23892497 | 0.75 | PRMT5 (0.32) | METTL3 | |
| SCHEMBL25948966 | 0.74 | ABL1 (0.37) | JAK3GPR119 | |
| SCHEMBL23892335 | 0.74 | ABL1 (0.37) | JAK3GPR119 | |
| SCHEMBL23892484 | 0.74 | P2RX1 (0.36) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219496-A1 | NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |