Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038219 | 1.00 | ATM (0.36) | ATML3MBTL1NCF1GAAPOLB | |
| SCHEMBL178803 | 0.91 | NCF1 (0.39) | NCF1ALDH1A1HTR2AHRH3 | |
| SCHEMBL14985398 | 0.82 | ATM (0.47) | ATML3MBTL1GAAPOLBHTR7 | |
| SCHEMBL14985380 | 0.82 | ATM (0.47) | ATML3MBTL1GAAPOLBHTR7 | |
| SCHEMBL9230772 | 0.82 | ATM (0.47) | ATML3MBTL1GAAPOLBHTR7 | |
| SCHEMBL22142247 | 0.79 | L3MBTL1 (0.37) | ATML3MBTL1NCF1ALDH1A1HRH3 | |
| SCHEMBL10236411 | 0.79 | L3MBTL1 (0.37) | ATML3MBTL1NCF1ALDH1A1HRH3 | |
| SCHEMBL6889570 | 0.78 | ALDH1A1 (0.42) | L3MBTL1NCF1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14930346 | 0.76 | NCF1 (0.36) | ATML3MBTL1NCF1GAAPOLB | |
| SCHEMBL14022396 | 0.76 | NCF1 (0.36) | ATML3MBTL1NCF1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |