Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888683 | 1.00 | THRB (0.62) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL14388243 | 0.96 | THRB (0.59) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL13569224 | 0.96 | THRB (0.59) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL8721132 | 0.96 | THRB (0.59) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL13806112 | 0.90 | THRB (0.71) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL14747621 | 0.90 | THRB (0.71) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL1115744 | 0.90 | THRB (0.71) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL12544895 | 0.87 | THRB (0.50) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL9301671 | 0.87 | THRB (0.77) | THRBLMNAALDH1A1USP2CYP3A4 | |
| SCHEMBL28504876 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |