SCHEMBL9301671

SCHEMBL9301671

OCCC(O)CC(O)CCC(O)CO

nearest known ligand 0.77

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.77
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
USP2 O75604 2/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14747621 0.91 THRB (0.71) THRBLMNAALDH1A1USP2CYP3A4
SCHEMBL1115744 0.91 THRB (0.71) THRBLMNAALDH1A1USP2CYP3A4
SCHEMBL13806112 0.91 THRB (0.71) THRBLMNAALDH1A1USP2CYP3A4
SCHEMBL4602198 0.88 THRB (0.87) THRBLMNAALDH1A1DPP4
SCHEMBL709962 0.87
SCHEMBL1888683 0.87 THRB (0.62) THRBLMNAALDH1A1USP2CYP3A4
SCHEMBL25949401 0.87 THRB (0.62) THRBLMNAALDH1A1USP2CYP3A4
SCHEMBL29798 0.87
SCHEMBL705919 0.87
SCHEMBL14388243 0.84 THRB (0.59) THRBLMNAALDH1A1USP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276174-A Alk-1-enyloxy carbonates ISP INVESTMENTS INC. (US) 1994-01-04 US disclosed
EP-0514482-A4 VINYL ETHER COMPOUNDS 1993-04-21 EP disclosed
EP-0514482-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1992-11-25 EP disclosed
WO-1991013052-A1 VINYL ETHER COMPOUNDS ISP INVESTMENTS INC. (US) 1991-09-05 WO disclosed