Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25950158 | 0.90 | LMNA (0.45) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950203 | 0.86 | LMNA (0.40) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950231 | 0.85 | CYP3A4 (0.42) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950164 | 0.85 | LMNA (0.45) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950226 | 0.81 | PDK1 (0.41) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950132 | 0.81 | LMNA (0.54) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL17308098 | 0.80 | LMNA (0.49) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950143 | 0.80 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL17308099 | 0.77 | LMNA (0.46) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL25950207 | 0.77 | TDP1 (0.40) | NPC1RAB9AMAPTALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725079-B2 | Polyimide compositions and articles incorporating the same | THE BOEING COMPANY (US) | 2023-08-15 | — | — | US | disclosed |