Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25950226 | 0.89 | PDK1 (0.41) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25950158 | 0.86 | LMNA (0.45) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL25950164 | 0.86 | LMNA (0.45) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25950199 | 0.84 | TDP1 (0.38) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25950231 | 0.81 | CYP3A4 (0.42) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL25950124 | 0.81 | RAB9A (0.40) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25950171 | 0.78 | ADRB2 (0.37) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL25950210 | 0.77 | LMNA (0.46) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL21185910 | 0.76 | TDP1 (0.52) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL25950143 | 0.76 | LMNA (0.47) | TDP1RAB9AALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725079-B2 | Polyimide compositions and articles incorporating the same | THE BOEING COMPANY (US) | 2023-08-15 | — | — | US | disclosed |