SCHEMBL25950249

SCHEMBL25950249

COCOc1ccc(Cc2c(C)cc(OS(=O)(=O)C(F)(F)F)c(F)c2Cl)cc1C(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.35
THRA P10827 8/20 0.35
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25950138 0.87 THRB (0.37) THRBTHRA
SCHEMBL25950388 0.87 THRB (0.38) THRBTHRA
SCHEMBL4214383 0.87 THRB (0.37) THRBTHRAOPRK1
SCHEMBL666840 0.86 THRB (0.46) THRBTHRAOPRK1
SCHEMBL25950022 0.85 THRB (0.42) THRBTHRAOPRK1
SCHEMBL25950182 0.80 THRB (0.36) THRBTHRAOPRK1
SCHEMBL3156780 0.80 THRB (0.46) THRBTHRAOPRK1
SCHEMBL25950186 0.79 THRB (0.36) THRBTHRA
SCHEMBL283312 0.78 THRB (0.33) THRBTHRA
SCHEMBL666663 0.75 THRB (0.47) THRBTHRAOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242471-A1 THYROMIMETICS AUTOBAHN THERAPEUTICS, INC. 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242471-A1 THYROMIMETICS TPO, THOP1, THRB THRB 3/4885THRA 6/4885OPRK1 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.