⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25950451 | 0.87 | — | — | |
| SCHEMBL25949866 | 0.85 | THRB (0.33) | — | |
| SCHEMBL25950412 | 0.82 | THRA (0.33) | — | |
| SCHEMBL25950450 | 0.78 | — | — | |
| SCHEMBL8130797 | 0.76 | — | — | |
| SCHEMBL24449999 | 0.74 | THRA (0.33) | — | |
| SCHEMBL8478227 | 0.73 | — | — | |
| SCHEMBL30286027 | 0.72 | THRB (0.34) | — | |
| SCHEMBL24132738 | 0.72 | THRB (0.34) | — | |
| SCHEMBL25949868 | 0.70 | THRB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |