⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25950414 | 0.87 | — | — | |
| SCHEMBL25950450 | 0.84 | — | — | |
| SCHEMBL25950412 | 0.78 | THRA (0.33) | — | |
| SCHEMBL8130797 | 0.75 | — | — | |
| SCHEMBL8478227 | 0.72 | — | — | |
| SCHEMBL25949866 | 0.71 | THRB (0.33) | — | |
| SCHEMBL25950449 | 0.68 | CLCN2 (0.31) | — | |
| SCHEMBL15303406 | 0.66 | BACE1 (0.34) | — | |
| SCHEMBL25949868 | 0.65 | THRB (0.38) | — | |
| SCHEMBL8480203 | 0.64 | ALK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |