Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | THRA | P10827 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 4/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PPIB | P23284 | 1/20 | 0.30 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | PPID | Q08752 | 1/20 | 0.30 |
| ▸ | PPIG | Q13427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25950176 | 0.93 | THRB (0.36) | THRBTHRAMAPTLTA4HGAA | |
| SCHEMBL25950435 | 0.90 | THRB (0.43) | THRBTHRA | |
| SCHEMBL25949875 | 0.88 | THRB (0.44) | THRBTHRALTA4HADRB3GAA | |
| SCHEMBL25950470 | 0.86 | CLCN2 (0.31) | MAPTGAA | |
| SCHEMBL25950443 | 0.81 | THRB (0.39) | THRBTHRA | |
| SCHEMBL24133137 | 0.79 | THRB (0.48) | THRBTHRA | |
| SCHEMBL25950441 | 0.77 | THRB (0.38) | THRBTHRA | |
| SCHEMBL25950467 | 0.75 | CLCN2 (0.35) | THRBTHRA | |
| SCHEMBL25950186 | 0.75 | THRB (0.36) | THRBTHRA | |
| SCHEMBL23462597 | 0.74 | THRB (0.45) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | THRB 3/4885THRA 6/4885MAPT 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.