Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31072338 | 0.82 | SRC (0.38) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL31072339 | 0.82 | SRC (0.38) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL6055183 | 0.80 | SIGMAR1 (0.37) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| Malonic Acid SCHEMBL11137101 | 0.79 | SIGMAR1 (0.42) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL3805977 | 0.79 | CYP1A2 (0.40) | SIGMAR1MEN1KMT2AATMLMNA | |
| SCHEMBL668104 | 0.77 | SIGMAR1 (0.38) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL29658875 | 0.77 | SIGMAR1 (0.41) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL29603716 | 0.77 | SIGMAR1 (0.38) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL28003595 | 0.77 | SIGMAR1 (0.38) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 | |
| SCHEMBL5597184 | 0.77 | SIGMAR1 (0.41) | P2RX4P2RX1P2RX3P2RX7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |