Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658875 | 1.00 | SIGMAR1 (0.41) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL7656352 | 0.98 | SIGMAR1 (0.40) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Ethylene SCHEMBL10454556 | 0.94 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL29603716 | 0.87 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL668104 | 0.87 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL28003595 | 0.87 | SIGMAR1 (0.38) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Glycerin SCHEMBL6838628 | 0.86 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL6904952 | 0.85 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| SCHEMBL9144870 | 0.85 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 | |
| Lithium SCHEMBL8770699 | 0.85 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445670-B2 | Combinatorial library approach to iminocyclitols with biological activity | UNITED THERAPEUTICS CORPORATION (US) | 2013-05-21 | — | — | US | claimed |
| EP-1244608-A4 | ALLYL ALCOHOL HYDROFORMYLATION | ARCO CHEM TECH (US) | 2005-08-03 | — | — | EP | claimed |
| EP-0993478-B1 | OLEFIN POLYMERIZATION PROCESS | BOREALIS TECH OY (FI) | 2004-04-07 | — | — | EP | claimed |
| JP-2003519203-A | — | — | 2003-06-17 | — | — | JP | claimed |
| EP-1244608-A1 | ALLYL ALCOHOL HYDROFORMYLATION | ARCO Chemical Technology, L.P. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001049643-A1 | ALLYL ALCOHOL HYDROFORMYLATION | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 2001-07-12 | — | — | WO | claimed |
| US-5654454-A | REDUCING UNSATURATED SUBSTITUENTS; USED FOR ADDITION POLYMERIZATION OF OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1997-08-05 | — | — | US | claimed |
| US-5510540-A | FOR SENSITIVE, HIGH RESOLUTION, RAPID HARDENING PHOTORESISTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | claimed |
| US-4851494-A | MOLDING, COATING | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | claimed |
| US-12398167-B2 | Process for producing metallocenes | LANXESS ORGANOMETALLICS GMBH (DE) | 2025-08-26 | — | — | US | disclosed |
| US-20250002519-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2025-01-02 | — | — | US | disclosed |
| US-12071445-B2 | Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same | YALE UNIVERSITY (US) | 2024-08-27 | — | — | US | disclosed |
| US-20230203077-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2023-06-29 | — | — | US | disclosed |
| US-11661465-B2 | Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-05-30 | — | — | US | disclosed |
| WO-1999003805-A1 | METHOD OF MAKING 2,6-DIMETHYLNAPHTHALENE FROM OTHER DIMETHYLNAPHTHALENE ISOMERS AND FROM DIMETHYLTETRALINS/DIMETHYLDECALINS WITH A METHYL GROUP ON EACH RING | CHEVRON CHEMICAL COMPANY LLC (US) | 1999-01-28 | — | — | WO | disclosed |
| US-5824752-A | Process for the preparation of advanced resins | SHELL OIL COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0745607-A2 | Metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5091439-A | Using arene iron complex as curing agent | CIBA-GEIGY CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-4962253-A | Vinylation of aromatics catalyzed by cyclopentadienyl, indenyl, or fluorenyl rhodium complexes, and novel indenyl and fluorenyl rhodium complexes | THE DOW CHEMICAL COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4861806-A | PHOTOPOLYMERIZATION, LATENCY | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002519-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | SIGMAR1 4517/4885HTR2A 4553/4885HTR6 4256/4885 |
| US-12398167-B2 | Process for producing metallocenes | CYP4F2, PRDX2, PRXL2A | SIGMAR1 4239/4885HTR2A 3539/4885HTR6 4463/4885 |
| US-20230203077-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | SIGMAR1 4517/4885HTR2A 4553/4885HTR6 4256/4885 |
| US-11661465-B2 | Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith | NONO, TPR, ZNF787 | SIGMAR1 1567/4885HTR2A 1640/4885HTR6 2234/4885 |
| US-12071445-B2 | Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same | TIMCC, YAP1, TET2 | SIGMAR1 4695/4885HTR2A 4606/4885HTR6 4201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.