Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156347 | 0.80 | NPC1 (0.40) | TDP1KDM4ENPC1POLBPTK2B | |
| SCHEMBL3359002 | 0.78 | P2RX7 (0.46) | TDP1KDM4ENPC1POLBPTK2B | |
| Hydrochloric Acid SCHEMBL9601743 | 0.74 | KDM4E (0.53) | TDP1KDM4EBLMKMT2AGAA | |
| SCHEMBL10040004 | 0.74 | KDM4E (0.48) | KDM4ENSD2MEN1KMT2APOLB | |
| SCHEMBL2173729 | 0.72 | CA2 (0.55) | KDM4ENPC1POLBPTK2BALDH1A1 | |
| SCHEMBL29733396 | 0.72 | CA2 (0.55) | KDM4ENPC1POLBPTK2BALDH1A1 | |
| SCHEMBL9225167 | 0.71 | NPC1 (0.34) | NPC1POLBPTK2BALDH1A1RAB9A | |
| SCHEMBL20182011 | 0.70 | KDM4E (0.48) | TDP1KDM4EPOLBALDH1A1CA2 | |
| SCHEMBL738492 | 0.70 | NPC1 (0.40) | KDM4EMEN1KMT2AGAANPC1 | |
| SCHEMBL4583539 | 0.70 | KDM4E (0.42) | TDP1KDM4EBLMNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142848-A2 | NANOPARTICLE ELECTRODES AND METHODS OF PREPARATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-11-17 | — | — | WO | disclosed |