Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498153 | 0.92 | ALDH1A1 (0.42) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16467923 | 0.88 | LMNA (0.50) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16468408 | 0.87 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2ACYP1A2CYP2D6 | |
| SCHEMBL16467937 | 0.87 | LPAR1 (0.44) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16468418 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL18994885 | 0.86 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16467888 | 0.86 | SLC2A1 (0.49) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16467911 | 0.86 | SLC2A1 (0.49) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL16468173 | 0.86 | LMNA (0.49) | ALDH1A1LMNAKMT2AACHECYP1A2 | |
| SCHEMBL2589901 | 0.83 | NR1D1 (0.41) | NR1D1ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141716-A2 | PHARMACEUTICAL COMPOUNDS | SENTINEL ONCOLOGY LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |