Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31651838 | 0.84 | SIGMAR1 (0.45) | HTR6SIGMAR1HTR2CPIM1PIM3 | |
| SCHEMBL16434801 | 0.84 | SIGMAR1 (0.45) | HTR6SIGMAR1HTR2CPIM1PIM3 | |
| Hydrochloric Acid SCHEMBL16423084 | 0.83 | HTR2C (0.46) | HTR6SIGMAR1HTR2CPIM1PIM3 | |
| SCHEMBL23903929 | 0.78 | HTR2C (0.41) | HTR6SIGMAR1HTR2CPRMT5CDK9 | |
| SCHEMBL29947277 | 0.78 | HTR2C (0.41) | HTR6SIGMAR1HTR2CPRMT5CDK9 | |
| SCHEMBL171596 | 0.76 | PIM1 (0.51) | HTR6SIGMAR1HTR2CPIM1PIM3 | |
| SCHEMBL30454060 | 0.74 | HTR2C (0.51) | SIGMAR1HTR2CPIM1PIM3PIM2 | |
| SCHEMBL5341889 | 0.74 | HTR2C (0.51) | SIGMAR1HTR2CPIM1PIM3PIM2 | |
| SCHEMBL7940586 | 0.73 | SIGMAR1 (0.49) | SIGMAR1HTR2CPIM1PIM3PIM2 | |
| SCHEMBL14761633 | 0.73 | CDK9 (0.57) | SIGMAR1HTR2CPIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |