Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341889 | 1.00 | HTR2C (0.51) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL171110 | 0.81 | SIGMAR1 (0.49) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL14761633 | 0.81 | CDK9 (0.57) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL13490658 | 0.81 | SIGMAR1 (0.49) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL3453255 | 0.81 | HTR2C (0.51) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL171596 | 0.81 | PIM1 (0.51) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL7940586 | 0.81 | SIGMAR1 (0.49) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL31651838 | 0.81 | SIGMAR1 (0.45) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL16434801 | 0.81 | SIGMAR1 (0.45) | HTR2CSIGMAR1QDPRPIM1PIM3 | |
| SCHEMBL169395 | 0.80 | SIGMAR1 (0.66) | HTR2CSIGMAR1QDPRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |