SCHEMBL25955784

SCHEMBL25955784

O=C(O)c1cccc(C(c2ccc3c(c2)C(=O)OC3=O)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.43
TYMS P04818 1/20 0.40
CES2 O00748 1/20 0.40
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
MRGPRX4 Q96LA9 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KCNK3 O14649 1/20 0.37
NR4A2 P43354 1/20 0.37
KIF11 P52732 1/20 0.36
PDK2 Q15119 1/20 0.36
UNG P13051 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL28332838 0.92 CA12 (0.42) SRD5A2CES2CA12CA1CA4
SCHEMBL25955785 0.89 CA12 (0.42) SRD5A2CA12CA1CA4CA7
SCHEMBL6930468 0.84 CA12 (0.36) SRD5A2CA12CA1CA4CA7
SCHEMBL49774 0.84 ALOX15 (0.43) TYMSCA12CA1CA4CA7
SCHEMBL29420736 0.84 SRD5A2 (0.57) SRD5A2CES2AKR1C3AKR1C2MRGPRX4
SCHEMBL545227 0.84 SRD5A2 (0.57) SRD5A2CES2AKR1C3AKR1C2MRGPRX4
SCHEMBL14839213 0.83 RXRA (0.42) SRD5A2CA12CA1CA4CA7
SCHEMBL9505714 0.82 TYMS (0.42) TYMSCA12CA1CA4CA7
SCHEMBL15699450 0.82 AKR1C3 (0.51) AKR1C3MRGPRX4POLBMEN1KMT2A
SCHEMBL25955781 0.80 CA12 (0.44) TYMSMRGPRX4CA12CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023145758-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING PHTHALIC ACID DERIVATIVE, AND COMPOSITION ダイキン工業株式会社 2023-08-03 WO disclosed