Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17083541 | 0.95 | ALDH1A1 (0.48) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL8342617 | 0.95 | ALDH1A1 (0.43) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| Hydrogen Sulfide SCHEMBL21904608 | 0.93 | ALDH1A1 (0.42) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL16317802 | 0.92 | ALDH1A1 (0.38) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL235021 | 0.92 | ALDH1A1 (0.38) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL1003214 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL29696079 | 0.89 | ALDH1A1 (0.44) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL1326486 | 0.87 | NAAA (0.44) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL13258499 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HIF1ATP53CYP3A4MAPK1 | |
| SCHEMBL6418139 | 0.85 | THRB (0.41) | ALDH1A1HIF1ATP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119125335-A | In-vivo analysis method of polyorthoester and application thereof | 广东药科大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-112176722-A | Poly (p-phenylene benzobisoxazole) fiber spinning oil and preparation method thereof | 天津工业大学 | 2021-01-05 | — | — | CN | disclosed |
| US-9149426-B2 | Nanoparticle composition and methods to make and use the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-10-06 | — | — | US | disclosed |
| US-20130209566-A1 | NANOPARTICLE COMPOSITION AND METHODS TO MAKE AND USE THE SAME | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2013-08-15 | — | — | US | disclosed |
| US-20120149864-A1 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONICS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8133968-B2 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20110082275-A1 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONIC, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7875697-B2 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| EP-2044142-A2 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | Medtronic, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20080033140-A1 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. | 2008-02-07 | — | — | US | disclosed |
| US-5661181-A | Non-cyclic esters for pest control | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5508334-A | HIGH VISCOSITY BUTYLENE-ETHYLENE-STYRENE BLOCK POLYMER WITH PLASTICIZING OIL AND MINOR AMOUNTS OF HOMO- OR COPOLYMERS OF BUTADIENE, ISOPRENE, STYRENE, ETHYLENE, PROPYLENE AND/OR BUTYLENE | APPLIED ELASTOMERICS, INC. (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1996000118-A1 | NOVEL ULTRA-SOFT, ULTRA-ELASTIC GEL AIRFOILS | APPLIED ELASTOMERICS, INC. (US) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995013851-A1 | HUMDINGER, STRING SPINNING TOY | APPLIED ELASTOMERICS, INCORPORATED (US) | 1995-05-26 | — | — | WO | disclosed |
| US-5334646-A | Butylene-ethylene-styrene block terpolymer | APPLIED ELASTOMERICS, INC. (US) | 1994-08-02 | — | — | US | disclosed |
| WO-1993015767-A1 | IMPLANT THERAPY FOR BONE GROWTH STIMULATION | MERCK & CO., INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5217712-A | Controlled drug delivery, prosthetic tissues | MERCK & CO., INC. (US) | 1993-06-08 | — | — | US | disclosed |
| US-5047464-A | Crosslinked polyorthoesters; drug deliver; resilience | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0419156-A2 | Bioerodible thermoset elastomers | MERCK & CO. INC. (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4275174-A | METHYL METHACRYLATE-STYRENE COPOLYMER FORMED IN THE PRESENCE OF A POLYOL BORIC ACID ESTER | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-06-23 | — | — | US | disclosed |