SCHEMBL25958

SCHEMBL25958

Nc1cc(F)ccc1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.70
ALDH1A1 P00352 6/20 0.58
KDM4E B2RXH2 5/20 0.58
HPGD P15428 1/20 0.58
HSD17B10 Q99714 1/20 0.58
PYGL P06737 1/20 0.52
TDP1 Q9NUW8 3/20 0.52
CYP3A4 P08684 2/20 0.52
ALOX15 P16050 1/20 0.52
PPM1B O75688 1/20 0.50
IDO1 P14902 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
KMT2A Q03164 3/20 0.47
GFER P55789 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
HDAC1 Q13547 2/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 2/20 0.45
THRB P10828 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9651484 0.98 KEAP1 (0.68) KEAP1ALDH1A1KDM4EHPGDHSD17B10
Nitrogen SCHEMBL28664597 0.96 KEAP1 (0.66) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL21857594 0.84 PPM1B (0.67) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL148542 0.83 KEAP1 (0.53) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL29364785 0.83 KEAP1 (1.00) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL135091 0.83 KEAP1 (1.00) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28303406 0.83 KEAP1 (0.53) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL12394324 0.81 KDM4E (0.66) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9117905 0.81 AHR (0.60) KEAP1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9000281 0.81 KEAP1 (0.96) KEAP1ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1805 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
CN-118497761-A Composition, and preparation method and application thereof 华为技术有限公司 2024-08-16 CN claimed
CN-113325036-B GO-MOF composite material, dimethylamine QCM sensor and preparation method thereof 重庆大学 2024-08-06 CN claimed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US claimed
US-20230349872-A1 GUN SHOT RESIDUE FIELD KIT VERITEQUE USA, INC. 2023-11-02 US claimed
CN-115010671-B One-step synthesis method of 2-substituted quinazolinone 江苏大学 2023-10-10 CN claimed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US claimed
EP-4182657-A1 GUN SHOT RESIDUE FIELD KIT Veriteque USA, Inc. (US) 2023-05-24 EP claimed
CN-116113822-A Bullet residue field kit 韦里特克美国有限公司 2023-05-12 CN claimed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP claimed
CN-103304492-A Synthesis method of EGFR (epidermal growth factor receptor) inhibitor Dacomitinib HUNAN OUYA BIOLOG CO LTD 2013-09-18 CN claimed
CN-103059001-A Quinazolinone Schiff base containing triazole and preparation method thereof JIANGSU RADIO AND TV UNIVERSITY 2013-04-24 CN claimed
CN-102702115-A Synthetic method of 4-chloro-7-fluoro-6-nitro quinazoline SHENGSHI TAIKE BIOMEDICAL TECHNOLOGY SUZHOU CO LTD 2012-10-03 CN claimed
CN-100522965-C 8-arylamine-3H-imidazole [4,5-g] quinazoline derivatives and its solid phase synthesis method ZHEJIANG UNIV OF TECHNOLOGY ZH (CN) 2009-08-05 CN claimed
CN-1948314-A 8-arylamine-3H-imidazole [4,5-g] quinazoline derivatives and its solid phase synthesis method UNIV ZHEJIANG TECHNOLOGY (CN) 2007-04-18 CN claimed
CN-1284773-C Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application BAIRUI GLOBAL CO LTD (VG) 2006-11-15 CN claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
WO-2003095417-A1 PROCESS FOR THE MANUFACTURE OF 4-FLUORO-ANTHRANILIC ACID MITENI S.P.A. (IT) 2003-11-20 WO claimed
US-5744638-A Process for the preparation of haloanthranilic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1998-04-28 US claimed