SCHEMBL135091

SCHEMBL135091

Nc1ccc(F)cc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 1.00
KDM4E B2RXH2 6/20 0.63
KMT2A Q03164 4/20 0.63
GFER P55789 1/20 0.63
RXFP1 Q9HBX9 1/20 0.63
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 3/20 0.61
MCL1 Q07820 2/20 0.61
USP2 O75604 2/20 0.61
MAPT P10636 2/20 0.61
THRB P10828 2/20 0.61
RECQL P46063 2/20 0.61
POLB P06746 1/20 0.61
PKM P14618 1/20 0.61
APEX1 P27695 1/20 0.61
BLM P54132 1/20 0.61
GLA P06280 1/20 0.59
ALDH1A1 P00352 7/20 0.57
CDC25B P30305 1/20 0.57
CASP6 P55212 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364785 1.00 KEAP1 (1.00) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL9000281 0.98 KEAP1 (0.96) KEAP1KDM4EKMT2AGFERRXFP1
Hydrochloric Acid SCHEMBL9653956 0.98 KEAP1 (0.96) KEAP1KDM4EKMT2AGFERRXFP1
Nitrogen SCHEMBL28928291 0.96 KEAP1 (0.92) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL2789012 0.84 KMT2A (0.78) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL183930 0.83 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL31230207 0.83 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL25958 0.83 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL9118879 0.81 KEAP1 (0.66) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL9665493 0.81 KEAP1 (0.68) KEAP1KDM4EKMT2AGFERRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
CN-119464351-A Method for improving CRISPR-Cas gene editing efficiency of yeast 大连理工大学 2025-02-18 CN claimed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US claimed
US-20230349872-A1 GUN SHOT RESIDUE FIELD KIT VERITEQUE USA, INC. 2023-11-02 US claimed
US-20230340539-A1 METHODS OF TRANSIENT PROTEIN AND GENE EXPRESSION IN CELLS ZYMERGEN INC. 2023-10-26 US claimed
CN-115010671-B One-step synthesis method of 2-substituted quinazolinone 江苏大学 2023-10-10 CN claimed
US-11718820-B2 Genetically modified haploid Issatchenkia orientalis CARGILL, INCORPORATED (US) 2023-08-08 US claimed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US claimed
CN-116283803-A Preparation method of flumazenil intermediate 上海旭东海普药业有限公司 2023-06-23 CN claimed
EP-4182657-A1 GUN SHOT RESIDUE FIELD KIT Veriteque USA, Inc. (US) 2023-05-24 EP claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
CN-1477097-A Preparation method of 2-amino-5-fluorobenzoic acid 华东理工大学 2004-02-25 CN claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
EP-0647614-B1 Process for the préparation of 5-fluoro anthranilic acid HOECHST AG (DE) 1997-06-04 EP claimed
EP-0647615-B1 Process for the preparation of 5-fluoroanthranilic acid alkyl esters and or 5-fluoroanthranilic acid HOECHST AG (DE) 1997-05-28 EP claimed
US-5543550-A NITRATING ALKYL ESTER OF 3-FLUOROBENZOIC ACID DISSOLVED IN SOLVENT-FREE SULFURIC ACID, THEN ADDING WATER, SEPARATION, HYDROLYSIS, PRESSURIZED CATALYTIC HYDROGENATION OF THE NITRATED ACID HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-06 US claimed
US-5523472-A Process for the preparation of 5-fluoroanthranilic acid HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-04 US claimed
EP-0700895-A2 Process for the selective preparation of fluorinated aromatic amines and fluorinated aromatic amines with particularly low contents of defluorinated portions BAYER AG (DE) 1996-03-13 EP claimed
EP-0647614-A1 Process for the préparation of 5-fluoro anthranilic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-12 EP claimed
EP-0647615-A1 Process for the preparation of 5-fluoroanthranilic acid alkyl esters and or 5-fluoroanthranilic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718820-B2 Genetically modified haploid Issatchenkia orientalis DERA, HOGA1, IPMK KEAP1 1092/4885KDM4E 2991/4885KMT2A 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.