SCHEMBL9000281

SCHEMBL9000281

Nc1ccc(F)cc1C(=O)O.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.96
KDM4E B2RXH2 6/20 0.61
KMT2A Q03164 4/20 0.61
GFER P55789 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
TDP1 Q9NUW8 3/20 0.59
MEN1 O00255 3/20 0.59
MCL1 Q07820 2/20 0.59
USP2 O75604 2/20 0.59
THRB P10828 2/20 0.59
RECQL P46063 2/20 0.59
POLB P06746 1/20 0.59
MAPT P10636 1/20 0.59
PKM P14618 1/20 0.59
APEX1 P27695 1/20 0.59
BLM P54132 1/20 0.59
GLA P06280 1/20 0.57
ALDH1A1 P00352 6/20 0.55
CDC25B P30305 1/20 0.55
CASP6 P55212 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135091 0.98 KEAP1 (1.00) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL29364785 0.98 KEAP1 (1.00) KEAP1KDM4EKMT2AGFERRXFP1
Hydrochloric Acid SCHEMBL9653956 0.96 KEAP1 (0.96) KEAP1KDM4EKMT2AGFERRXFP1
Nitrogen SCHEMBL28928291 0.94 KEAP1 (0.92) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL2789012 0.82 KMT2A (0.78) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL31230207 0.81 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL183930 0.81 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL25958 0.81 KEAP1 (0.70) KEAP1KDM4EKMT2AGFERRXFP1
SCHEMBL9118879 0.79 KEAP1 (0.66) KEAP1KDM4EKMT2AGFERRXFP1
Hydrochloric Acid SCHEMBL4362930 0.79 KEAP1 (0.68) KEAP1KDM4EKMT2AGFERRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523472-A Process for the preparation of 5-fluoroanthranilic acid HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed