Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208498 | 0.85 | ERN1 (0.47) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL24248444 | 0.77 | ERN1 (0.41) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL29950894 | 0.76 | ERN1 (0.40) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL29956526 | 0.74 | ERN1 (0.38) | ERN1CYP2A6PTGDR2ALDH1A1LMNA | |
| SCHEMBL3209434 | 0.73 | ERN1 (0.52) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL31457111 | 0.73 | ERN1 (0.52) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL29952087 | 0.72 | TSHR (0.40) | ERN1PTGDR2ALDH1A1ALDH1A3LMNA | |
| SCHEMBL15094082 | 0.71 | ALDH1A1 (0.60) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL31035488 | 0.71 | ERN1 (0.53) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 | |
| SCHEMBL3040456 | 0.71 | ERN1 (0.64) | ERN1CYP2A6PTGDR2PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |