Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956526 | 0.86 | ERN1 (0.38) | KDM4ERXFP1ERN1PTGDR2MEN1 | |
| SCHEMBL29957679 | 0.82 | NOTUM (0.39) | TSHRPTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL29950894 | 0.81 | ERN1 (0.40) | KDM4EERN1PTGDR2MEN1KMT2A | |
| SCHEMBL29956046 | 0.78 | MPO (0.38) | KDM4EERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL29958139 | 0.75 | ALDH1A3 (0.41) | TSHRKDM4EMAPK1ERN1PTGDR2 | |
| SCHEMBL29957388 | 0.75 | ALDH1A1 (0.37) | TSHRKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL29956412 | 0.73 | ERN1 (0.46) | KDM4EERN1KMT2AALDH1A1LMNA | |
| SCHEMBL29956220 | 0.73 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2L3MBTL1ALDH1A3 | |
| SCHEMBL25959321 | 0.72 | ERN1 (0.48) | ERN1PTGDR2ALDH1A1LMNAALDH1A3 | |
| SCHEMBL3208498 | 0.71 | ERN1 (0.47) | KDM4EMAPK1ERN1PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |