Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952087 | 0.86 | TSHR (0.40) | ERN1PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL29958139 | 0.85 | ALDH1A3 (0.41) | ERN1PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL29950894 | 0.83 | ERN1 (0.40) | ERN1PTGDR2MEN1KMT2AEGFR | |
| SCHEMBL2561856 | 0.81 | OPRM1 (0.41) | PTGDR2NOTUMMEN1KMT2AOPRM1 | |
| SCHEMBL24248444 | 0.78 | ERN1 (0.41) | ERN1PTGDR2MEN1KMT2AALDH1A1 | |
| SCHEMBL2557844 | 0.77 | ERN1 (0.37) | ERN1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL25959321 | 0.74 | ERN1 (0.48) | ERN1PTGDR2ALDH1A1CYP2A6LMNA | |
| SCHEMBL3208498 | 0.73 | ERN1 (0.47) | ERN1PTGDR2EGFRALDH1A1KDM4E | |
| SCHEMBL2554624 | 0.73 | ALDH1A1 (0.35) | NOTUMMEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL2556619 | 0.72 | ERN1 (0.48) | ERN1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |