Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395445 | 0.81 | ERN1 (0.42) | HTR2AHTR2CHTR2BMEN1ALDH1A1 | |
| SCHEMBL275497 | 0.81 | ERN1 (0.42) | HTR2AHTR2CHTR2BMEN1ALDH1A1 | |
| SCHEMBL25959726 | 0.77 | KDM4E (0.50) | HTR2AHTR2CHTR2BMEN1ALDH1A1 | |
| SCHEMBL25337943 | 0.77 | KDM4E (0.50) | HTR2AHTR2CHTR2BMEN1ALDH1A1 | |
| SCHEMBL15561272 | 0.76 | XDH (0.40) | HTR2AHTR2CHTR2BTUBB1MEN1 | |
| SCHEMBL7939404 | 0.76 | HTR2A (0.47) | HTR2AHTR2CHTR2BTUBB1MEN1 | |
| SCHEMBL23088455 | 0.73 | TUBB1 (0.41) | HTR2AHTR2CHTR2BTUBB1PTGS2 | |
| SCHEMBL34462731 | 0.73 | VCP (0.50) | ALDH1A1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL15594069 | 0.72 | HTR2A (0.45) | HTR2AHTR2CHTR2BTUBB1MEN1 | |
| SCHEMBL12804391 | 0.71 | HTR2A (0.44) | HTR2AHTR2CHTR2BTUBB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150374-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |