SCHEMBL31395445

SCHEMBL31395445

COc1ccc(Cl)c(F)c1C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.42
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
HTR2B P41595 2/20 0.41
ALDH1A1 P00352 7/20 0.40
CYP1A2 P05177 2/20 0.40
TSHR P16473 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GLA P06280 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37
S1PR4 O95977 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
G6PD P11413 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL275497 1.00 ERN1 (0.42) ERN1HTR2AHTR2CHTR2BALDH1A1
SCHEMBL1764794 0.85 ERN1 (0.42) ERN1HTR2AHTR2CHTR2BALDH1A1
SCHEMBL1478225 0.84 ERN1 (0.47) ERN1ALDH1A1TSHRTDP1KDM4E
SCHEMBL15561272 0.83 XDH (0.40) HTR2AHTR2CHTR2BALDH1A1CYP1A2
SCHEMBL13101273 0.82 ALDH1A1 (0.46) ERN1ALDH1A1CYP1A2TSHRCYP2C9
SCHEMBL5644897 0.82 CLCN2 (0.38) ERN1HTR2AHTR2CHTR2BALDH1A1
SCHEMBL25959720 0.81 HTR2A (0.41) HTR2AHTR2CHTR2BALDH1A1TSHR
SCHEMBL2415640 0.81 ERN1 (0.44) ERN1HTR2AHTR2CHTR2BALDH1A1
SCHEMBL911855 0.81 ERN1 (0.44) ERN1HTR2AHTR2CHTR2BALDH1A1
SCHEMBL30958030 0.81 TACR2 (0.40) ERN1ALDH1A1TSHRHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
WO-2025032440-A1 KLF2 INDUCING COMPOUNDS AND USES THEREOF PFIZER INC. (US) 2025-02-13 WO disclosed