SCHEMBL25960306

SCHEMBL25960306

CCC(C)(C)OC(=O)N1CCCC1C(=O)OC[SiH3]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 14/20 0.47
HSD17B10 Q99714 2/20 0.41
RAB9A P51151 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25960309 0.89 FKBP1A (0.52) FKBP1A
SCHEMBL25960270 0.88 HSD17B10 (0.53) FKBP1AHSD17B10RAB9AMEN1KMT2A
SCHEMBL12769056 0.82 RAB9A (0.55) HSD17B10RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL9893422 0.82 RAB9A (0.55) HSD17B10RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL440340 0.78 FKBP1A (0.58) FKBP1AHSD17B10MEN1KMT2ASMN1; SMN2
SCHEMBL8223617 0.78 FKBP1A (0.58) FKBP1AHSD17B10MEN1KMT2ASMN1; SMN2
SCHEMBL1401256 0.78 FKBP1A (0.58) FKBP1AHSD17B10MEN1KMT2ASMN1; SMN2
SCHEMBL12768307 0.77 NPC1 (0.52) FKBP1AMEN1KMT2AALDH1A1
SCHEMBL12873027 0.77 FKBP1A (0.66) FKBP1A
SCHEMBL25960272 0.76 FKBP1A (0.50) FKBP1AHSD17B10MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230244149-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-03 US disclosed