Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | CHAT | P28329 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587319 | 0.77 | RXRA (0.44) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4814070 | 0.75 | CHAT (0.44) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3247717 | 0.75 | RXRA (0.43) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18243277 | 0.75 | CYP2A6 (0.43) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27671615 | 0.72 | MTNR1A (0.45) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18242061 | 0.72 | RXRA (0.41) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18242247 | 0.72 | RXRA (0.41) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL947159 | 0.72 | GRIN2D (0.50) | RXRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10706687 | 0.71 | CHAT (0.62) | RXRACHATHSD17B10TSHRHDAC8 | |
| SCHEMBL816177 | 0.71 | TSHR (0.50) | RXRAGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006422-B2 | Oxidation process for preparing 3-formyl-cephem derivatives | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2015-04-14 | — | — | US | claimed |
| EP-2569321-B1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | BASILEA PHARMACEUTICA INTERNAT LTD (CH) | 2015-03-04 | — | — | EP | claimed |
| EP-2569321-A1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | Basilea Pharmaceutica International Ltd. (CH) | 2013-03-20 | — | — | EP | claimed |
| WO-2011141415-A1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2011-11-17 | — | — | WO | claimed |