SCHEMBL3247717

SCHEMBL3247717

FC(F)(F)[CH]c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.43
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
CHAT P28329 3/20 0.41
TSHR P16473 3/20 0.41
HSD17B10 Q99714 3/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP2A6 P11509 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18242247 0.83 RXRA (0.41) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18242262 0.80 HSD17B10 (0.40) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28422123 0.79 RXRA (0.49) RXRACHATHDAC8HDAC6ALDH1A1
SCHEMBL18243166 0.79 RXRA (0.38) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18243277 0.78 CYP2A6 (0.43) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4814070 0.78 CHAT (0.44) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2596074 0.75 RXRA (0.41) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL18242061 0.75 RXRA (0.41) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL426753 0.75 RXRA (0.47) RXRAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL123180 0.75 TSHR (0.48) RXRAGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233864-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-12-07 WO disclosed
WO-2023132318-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-07-13 WO disclosed
CN-110437046-B Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2022-08-16 CN disclosed
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
CN-107406584-B Fluorine atom-containing polymer and field of use thereof 日产化学工业株式会社 2020-06-09 CN disclosed
CN-110437046-A Polymer containing fluorine atom and its utilize technical field NISSAN CHEMICAL IND LTD 2019-11-12 CN disclosed
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
EP-0822544-B1 Optical recording medium MITSUI CHEMICALS INC (JP) 2001-01-03 EP disclosed
US-6162520-A Optical recording medium and dipyrromethene metal chelate compound for use therein MITSUI CHEMICALS, INC. (JP) 2000-12-19 US disclosed
US-6060606-A OPTICAL RECORDING MEDIUM HAVING AT LEAST A RECORDING LAYER AND A REFLECTIVE LAYER ON A SUBSTRATES; HIGH DENSITY, COMPACT DISKS MITSUI CHEMICALS, INC. (JP) 2000-05-09 US disclosed
EP-0755052-B1 Optical recording medium MITSUI CHEMICALS INC (JP) 1999-11-17 EP disclosed
CN-1218257-A Optical recording medium and dipyrromethene metal chelate compound for use therein MITSUI CHEMICALS INC (JP) 1999-06-02 CN disclosed
EP-0903733-A2 Optical recording medium and dipyrromethene metal chelate compound for use therein Mitsui Chemicals, Inc. (JP) 1999-03-24 EP disclosed
EP-0881636-A1 Optical recording medium Mitsui Chemicals, Inc. (JP) 1998-12-02 EP disclosed
CN-1175058-A Optical recording medium MITSUI TOATSU CHEMICALS (JP) 1998-03-04 CN disclosed
EP-0822544-A1 Optical recording medium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed
EP-0755052-A2 Optical recording medium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 RXRA 202/4885GRIN2D 3891/4885GRIN3B 4024/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 RXRA 1004/4885GRIN2D 3793/4885GRIN3B 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.