SCHEMBL25962015

SCHEMBL25962015

Clc1ccc2c(c1)-c1c(-c3ccccc3)cccc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.38
HSD11B1 P28845 3/20 0.36
PDK2 Q15119 4/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.33
FABP4 P15090 2/20 0.32
OPRK1 P41145 2/20 0.31
PDE4D Q08499 2/20 0.31
CHRM1 P11229 2/20 0.31
CNR1 P21554 1/20 0.31
NTSR1 P30989 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NR1I2 O75469 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
PTGS2 P35354 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25962200 0.90 SLC6A3 (0.35) SLC6A3HSD11B1PDK2PTGDR2
SCHEMBL23318634 0.87 HSD11B1 (0.38) HSD11B1PDK2CHRM1ALDH1A1
SCHEMBL23318635 0.87 SLC6A3 (0.38) SLC6A3HSD11B1PDK2ALDH1A1ADORA3
SCHEMBL23609590 0.86 TDP2 (0.39) HSD11B1PDK2
SCHEMBL23318795 0.86 SLC6A3 (0.37) SLC6A3HSD11B1PDK2ALDH1A1PTGS2
SCHEMBL30593282 0.86 PDK2 (0.40) SLC6A3HSD11B1PDK2NPSR1
SCHEMBL25582581 0.86 PDK2 (0.40) SLC6A3HSD11B1PDK2NPSR1
SCHEMBL23318889 0.85 PDK2 (0.39) HSD11B1PDK2CHRM1
SCHEMBL24618091 0.84 HSD11B1 (0.36) HSD11B1PDK2
SCHEMBL23609300 0.84 PDK2 (0.35) SLC6A3HSD11B1PDK2AKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142492-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-08-03 WO disclosed