Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | BCHE | P06276 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740197 | 0.79 | BCHE (0.39) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL2593078 | 0.77 | BCHE (0.59) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL8300989 | 0.70 | QDPR (0.45) | ACHEBCHECHRM2CHRM4CHRM5 | |
| SCHEMBL8300351 | 0.68 | SLC6A2 (0.59) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL29876097 | 0.66 | MAOA (0.44) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL28792227 | 0.66 | MAOA (0.44) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL4788341 | 0.66 | CA12 (0.49) | CA12CA1CA2CA9 | |
| SCHEMBL15530574 | 0.66 | HTR1D (0.39) | MAPK14MAPK11 | |
| SCHEMBL28792307 | 0.65 | SLC6A2 (0.53) | CA12CA1CA2CA9SLC6A2 | |
| SCHEMBL29876774 | 0.65 | SLC6A2 (0.53) | CA12CA1CA2CA9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566862-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | Bristol-Myers Squibb Company (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140161-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |