Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586133 | 0.86 | AVPR1A (0.33) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2550063 | 0.86 | NAMPT (0.40) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2587030 | 0.86 | GPR119 (0.32) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2538175 | 0.86 | HTR2A (0.39) | — | |
| SCHEMBL2580027 | 0.85 | DDB1 (0.36) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2580235 | 0.85 | OXTR (0.34) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2579657 | 0.85 | OXTR (0.36) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2565485 | 0.84 | FNTA (0.37) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2574746 | 0.84 | OXTR (0.34) | OXTRAVPR1ADDB1CRBNGPR119 | |
| SCHEMBL2579958 | 0.84 | OXTR (0.34) | OXTRAVPR1ADDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569319-A1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011141396-A1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-11-17 | — | — | WO | disclosed |