Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556747 | 0.91 | HDAC1 (0.38) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2579657 | 0.90 | OXTR (0.36) | DDB1CRBNAVPR1AOXTRGPR119 | |
| SCHEMBL2565904 | 0.90 | AVPR2 (0.37) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2552066 | 0.89 | GPR119 (0.38) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2549514 | 0.89 | MGLL (0.35) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2580027 | 0.88 | DDB1 (0.36) | DDB1CRBNAVPR1AOXTRGPR119 | |
| SCHEMBL2578140 | 0.88 | TACR1 (0.34) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2565485 | 0.88 | FNTA (0.37) | DDB1CRBNAVPR1AOXTRGPR119 | |
| SCHEMBL2574746 | 0.88 | OXTR (0.34) | NAMPTDDB1CRBNAVPR1AOXTR | |
| SCHEMBL2580300 | 0.88 | OXTR (0.36) | DDB1CRBNAVPR1AOXTRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552919-A1 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. Hoffmann-La Roche AG (CH) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120877-A1 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-10-06 | — | — | WO | disclosed |