Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.69 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | TDP2 | O95551 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977422 | 0.85 | KDM1A (0.71) | KDM1AKIF11GRIA2KCNH2LMNA | |
| SCHEMBL15866459 | 0.83 | OPRM1 (0.52) | KDM1AKIF11LMNAKDM4EALDH1A1 | |
| SCHEMBL8028031 | 0.83 | GRIA2 (0.65) | KDM1AKIF11GRIA2KCNH2TDP2 | |
| SCHEMBL15137074 | 0.82 | KDM1A (1.00) | KDM1AKIF11GRIA2KCNH2 | |
| SCHEMBL15136959 | 0.82 | KDM1A (1.00) | KDM1AKIF11GRIA2KCNH2 | |
| SCHEMBL15136544 | 0.82 | KDM1A (1.00) | KDM1AKIF11GRIA2KCNH2 | |
| SCHEMBL20924219 | 0.81 | KDM1A (0.73) | KDM1AUSP2CYP1A2CYP3A4MAPK1 | |
| SCHEMBL21092440 | 0.81 | KIF11 (0.69) | KDM1AKIF11TDP2BRD4LMNA | |
| Hydrochloric Acid SCHEMBL15136418 | 0.81 | KDM1A (0.97) | KDM1AKIF11GRIA2KCNH2 | |
| Hydrochloric Acid SCHEMBL15136417 | 0.81 | KDM1A (0.97) | KDM1AKIF11GRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495349-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2023-06-28 | — | — | EP | disclosed |