Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 11/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.61 |
| ▸ | KDM1A | O60341 | 5/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25964972 | 0.83 | KDM1A (0.69) | GRIA2KCNH2KDM1AKIF11USP2 | |
| SCHEMBL13977422 | 0.81 | KDM1A (0.71) | GRIA2KCNH2KDM1AKIF11LMNA | |
| SCHEMBL13297258 | 0.79 | GRIA2 (1.00) | GRIA2KCNH2CYP1A2CYP2C19 | |
| SCHEMBL4607295 | 0.79 | GRIA2 (0.73) | GRIA2KCNH2KDM1A | |
| SCHEMBL14141327 | 0.79 | GRIA2 (0.73) | GRIA2KCNH2KDM1A | |
| SCHEMBL4605918 | 0.79 | GRIA2 (0.73) | GRIA2KCNH2KDM1A | |
| SCHEMBL6239372 | 0.77 | GRIA2 (0.60) | GRIA2KCNH2KDM1AKIF11USP2 | |
| SCHEMBL8019550 | 0.76 | GRIA4 (0.54) | GRIA2KDM1A | |
| SCHEMBL5185927 | 0.76 | GRIA2 (0.71) | GRIA2KCNH2KDM1AKIF11TDP2 | |
| SCHEMBL4956505 | 0.76 | GRIA2 (1.00) | GRIA2KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092712-A1 | COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-07-30 | — | — | WO | disclosed |