SCHEMBL2596673

SCHEMBL2596673

O=Cc1cccc(C(Cl)Cl)c1C(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.42
▸ LMNA P02545 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ THRB P10828 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ ERN1 O75460 4/20 0.38
▸ TLR2 O60603 1/20 0.36
▸ TLR1 Q15399 1/20 0.36
▸ TLR6 Q9Y2C9 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ ALDH1A1 P00352 4/20 0.35
▸ TRIM24 O15164 2/20 0.35
▸ TRIM33 Q9UPN9 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ CYP2A6 P11509 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5808127 0.80 LMNA (0.55) KMT2ALMNAMEN1TDP1THRB
SCHEMBL6819433 0.78 MEN1 (0.41) KMT2ALMNAMEN1TDP1THRB
SCHEMBL29472311 0.71 LMNA (0.42) KMT2ALMNAMEN1TDP1THRB
SCHEMBL5473286 0.71 LMNA (0.42) KMT2ALMNAMEN1TDP1THRB
SCHEMBL10594834 0.68 LMNA (0.50) KMT2ALMNAMEN1TDP1THRB
SCHEMBL11769827 0.68 LMNA (0.50) KMT2ALMNAMEN1TDP1THRB
SCHEMBL6820110 0.68 MEN1 (0.39) KMT2ALMNAMEN1TDP1THRB
SCHEMBL7306128 0.66 TSHR (0.36) LMNABLMCA1CA2ALDH1A1
SCHEMBL9654617 0.65 LMNA (0.41) KMT2ALMNAMEN1TDP1THRB
SCHEMBL10930855 0.65 LMNA (0.46) KMT2ALMNAMEN1TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865917-B2 Hardeners for thermosettable resin compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2014-10-21 — — US disclosed
US-20130066026-A1 HARDENERS FOR THERMOSETTABLE RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-03-14 — — US disclosed
WO-2011146106-A1 HARDENERS FOR THERMOSETTABLE RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066026-A1 HARDENERS FOR THERMOSETTABLE RESIN COMPOSITIONS ARID2, ASH2L, AAAS KMT2A 314/4885LMNA 2128/4885MEN1 4122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback