Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
| ▸ | FLT4 | P35916 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969706 | 0.75 | MGLL (0.43) | SLC6A9MGLL | |
| SCHEMBL20613072 | 0.74 | SLC6A9 (0.41) | EGFRFGFR1FLT1FLT4KDR | |
| SCHEMBL25968959 | 0.70 | FFAR4 (0.37) | EGFRFGFR1FLT1FLT4KDR | |
| SCHEMBL20613067 | 0.69 | EGFR (0.42) | EGFRFGFR1FLT1FLT4KDR | |
| SCHEMBL20597188 | 0.69 | SGK1 (0.34) | — | |
| SCHEMBL20713925 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL13419330 | 0.67 | EGFR (0.53) | EGFRFGFR1FLT1FLT4KDR | |
| SCHEMBL25968327 | 0.67 | SLC6A9 (0.41) | EGFRFGFR1FLT1FLT4KDR | |
| SCHEMBL13419313 | 0.67 | BPTF (0.43) | LMNAMAPTHTT | |
| SCHEMBL20613076 | 0.67 | SLC6A9 (0.39) | EGFRFGFR1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |