Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15201483 | 0.80 | PDE3B (0.39) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL30197316 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL843559 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| Ammonia Solution, Strong SCHEMBL27851817 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL28363572 | 0.77 | TYMS (0.36) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL11713155 | 0.77 | MAPT (0.45) | ALDH1A1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL18032590 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL2972185 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL31481292 | 0.77 | GPR35 (0.44) | ALDH1A1TDP1KMT2AMEN1TSHR | |
| SCHEMBL2596971 | 0.77 | GPR35 (0.44) | ALDH1A1TDP1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410125-A | Preparation method of 2-methyl-3-nitro-4-hydroxypyridine | 嘉兴逸泰生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-109476635-A | For treating the disubstituted pyrazole class compound of disease | FGH生物科技公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108883099-A | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | 石全 | 2018-11-23 | — | — | CN | disclosed |
| CN-107847498-A | tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107406462-A | Tricyclic DLK inhibitors and uses thereof | 豪夫迈·罗氏有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107250110-A | The noval chemical compound of (RET) inhibitor is reset as transfection | 葛兰素史克知识产权发展有限公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-107106561-A | Heparan sulfate biosynthesis inhibitor for treating disease | 生物马林药物股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103261198-B | 2-Aryimidazole is also [1,2-a] pyridine and also [1,2-a] pyrazines derivatives of 2-phenylimidazole of [1,2-b] pyridazine, 2-phenylimidazole also | 江苏恒瑞医药股份有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105579452-A | New 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV | 2016-05-11 | — | — | CN | disclosed |
| CN-102574845-B | 1H-imidazo [4,5-c] qualone derivative | NOVARTIS AG (CH) | 2015-09-02 | — | — | CN | disclosed |
| CN-104603134-A | Amido-benzyl sulfone and sulfoxide derivatives | GENENTECH INC | 2015-05-06 | — | — | CN | disclosed |
| CN-104520290-A | Amido spirocyclic amide and sulfonamide derivatives | GENENTECH INC | 2015-04-15 | — | — | CN | disclosed |
| CN-104507936-A | Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives | FORMA TM LLC | 2015-04-08 | — | — | CN | disclosed |
| CN-103189377-B | N1/n2-lactam acetyl-coa carboxylase inhibitors | PFIZER | 2015-02-25 | — | — | CN | disclosed |
| CN-102695708-B | N1-pyrazolospiroketone acetyl-coA carboxylase inhibitors | PFIZER INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-102459272-B | Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use | GENENTECH INC | 2014-08-06 | — | — | CN | disclosed |
| US-20130324528-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | US | disclosed |
| CN-102574845-A | 1h-imidazo[4,5-c]quinolinone derivatives | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |
| CN-102459272-A | Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use | GENENTECH INC | 2012-05-16 | — | — | CN | disclosed |
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324528-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | ALK, ALKBH5, ALKBH3 | ALDH1A1 134/4885TDP1 1648/4885KMT2A 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.